Clinical Efficacy of Short Term Low Dose Glucocorticoids Combined with Azithromycin in Children with Bronchopneumonia
Objective To explore the clinical effect of short term low dose glucocorticoids combined with azithromycin on children with bronchial pneumonia.Methods A total of 100 children with bronchopneumonia admitted to the Huxi Hospital Affiliated to Jining Medical College from March 2022 to March 2023 were selected as the study objects,and randomly divided into a control group and an experimental group,with 50 cases in each group.The control group was treated with azithromycin,and the experimental group was treated with short term low dose glucocorticoids based on the control group.The clinical efficacy,disappearance time of clinical symptoms and signs,levels of inflammatory factors,lung function indexes and adverse reactions were compared between the two groups.Results The total effective rate of the experimental group was 86.00%,which was higher than 20.00%of the control group,and the time of fever,lung moist rales,cough and lung shadow were shorter than that of the control group,the differences were statistically significant(P<0.05).Before treatment,there were no statistical significance in the levels of inflammatory factors and pulmonary function indexes between the two groups(P>0.05);after treatment,C-reactive protein and interleukin-6 in the experimental group were lower than those in the control group,and the maximum expiratory volume in the first second and forced vital capacity in the experimental group were higher than those in the control group,the differences between groups were statistically significant(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion Short term low dose glucocorticoids combined with azithromycin therapy is effective in children with bronchoppneumonia,speeding up symptom relief,reducing inflammatory response,improving lung function,and has good safety.
BronchopneumoniaGlucocorticoidAzithromycinCurative effectLung function
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