首页|美沙拉嗪联合中药灌肠序贯疗法治疗溃疡性结肠炎患者的临床效果观察

美沙拉嗪联合中药灌肠序贯疗法治疗溃疡性结肠炎患者的临床效果观察

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目的 探讨美沙拉嗪联合中药灌肠序贯疗法治疗溃疡性结肠炎患者的临床效果.方法 选取 2022 年3 月—2024 年5 月苏州市吴江区中医医院收治的 60 例溃疡性结肠炎患者为研究对象,按随机数字表法将其分为对照组和观察组,每组30例.对照组采用美沙拉嗪联合西药灌肠治疗,观察组采用美沙拉嗪联合中药灌肠序贯疗法治疗.比较两组的临床疗效、疾病活动程度、生活质量.结果 治疗前,两组疾病活动程度、生活质量比较,组间差异无统计学意义(P>0.05);治疗后,观察组Mayo指数积分低于对照组,炎症性肠病生活质量问卷评分高于对照组,组间差异有统计学意义(P<0.05).观察组治疗总有效率为 96.67%,高于对照组的 73.33%,差异有统计学意义(P<0.05).结论 美沙拉嗪联合中药灌肠序贯疗法治疗溃疡性结肠炎患者的临床效果较好,能有效改善其症状,提升患者生活质量.
Observation on the Clinical Efficacy of Mesalazine Combined with Chinese Medicine Enema Sequential Therapy in the Treatment of Patients with Ulcerative Colitis
Objective To explore the observation on the clinical effects of the mesalazine combined with Chinese medicine enema sequential therapy in the treatment of patients with ulcerative colitis.Methods Sixty patients with ulcerative colitis who were admitted to Suzhou Wujiang District Hospital of Traditional Chinese Medicine from March 2022 to May 2024 were selected as the research objects,according to the random number table method,they were divided into a control group and an observation group,with 30 cases in each group.The control group was treated with mesalazine combined with Western medicine enema,while the observation group was treated with the mesalazine combined with Chinese medicine enema sequential therapy.Compare the clinical efficacy,degree of disease activity and quality of life between the two groups.Results Before treatment,the degree of disease activity and quality of life of the two groups were compared,and the differences between the groups were no statistically significant(P>0.05);after treatment,the Mayo index score in the observation group was lower than that in the control group,while the score of the Inflammatory Bowel Disease Questionnaire in the observation group was higher than that in the control group,and the differences between the groups were statistically significant(P<0.05).The total effective rate of treatment in the observation group was 96.67%,which was higher than 73.33%in the control group,and the difference was statistically significant(P<0.05).Conclusion The mesalazine combined with Chinese medicine enema sequential therapy has a good clinical effect in treating patients with ulcerative colitis,it can effectively relieve their symptoms and improve the patients'quality of life.

Ulcerative colitisChinese medicine enema sequential therapyMesalazineQuality of life

周静

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苏州市吴江区中医医院(苏州市吴江区第二人民医院)脾胃病科,江苏 苏州 215221

溃疡性结肠炎 中药灌肠序贯疗法 美沙拉嗪 生活质量

2024

反射疗法与康复医学

反射疗法与康复医学

ISSN:
年,卷(期):2024.5(14)