Observation of the Clinical Efficacy of Budesonide Nebulized Inhalation Combined with Sequential Treatment with Azithromycin for Children with Mycoplasma Pneumoniae Pneumonia
Objective To investigate the effect of budesonide hebulized inhalation combined with sequential treatment with azithromycin on children with mycoplasma peumoniae pneumonia(MPP).Methods A total of 416 children with MPP admitted to Laiyang Central Hospital of Yantai City from August 2022 to March 2023 were selected as the research objects,and were divided into a control group and an observation group according to random number table method,with 208 cases in each group.The control group received sequential treatment with azithromycin,and the observation group received combined treatment with budesonide nebulized inhalation on the basis of the control group.The clinical efficacy,pulmonary function indicators and the occurrence of adverse reactions were compared between the two groups.Results The total effective rate of the observation group was 94.23%,which was higher than 82.69%of the control group,and the difference was statistically significant(P<0.05).After treatment,the forced vital capacity and forced expiratory volume at the first second in the observation group were higher than those in the control group,and the maximum expiratory flow rate was faster than that in the control group,with statistical significance(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion The budesonide nebulized inhalation combined with sequential treatment with azithromycin has significant clinical effect on MPP children,and can improve lung function with good safety.
Mycoplasma pneumoniae pneumoniaBudesonideSequential treatment with azithromycinClinical efficacy