Effect of Ambroterol Assisted Cefaclor in the Treatment of Acute Bronchitis in Children
Objective To explore the specific effect of ambroterol assisted cefaclor in the treatment of acute bronchitis in children.Methods Seventy-four children with acute bronchitis admitted to our hospital from January 2021 to January 2024 were selected as the research subjects.They were randomly divided into a control group and an observation group using a random number table method on this basis, with 37 cases in each group.The control group was treated with cefaclor, and the observation group was treated with ambroterol on this basis.After 1 week of treatment, the clinical efficacy, serum inflammatory factor levels, blood gas indexes and adverse reactions were compared between the two groups.Results The total effective rate of the observation group was 97.30％, higher than 78.38％ of the control group, and the difference was statistically significant (P<0.05).After treatment, the levels of tumor necrosis factor-α(TNF-α), interleukin-6 (IL-6), and interleukin-1β(IL-1β) in both groups were lower than before treatment, and the observation group were lower than the control group, the difference were statistically significant(P<0.05).After treatment, the levels of blood oxygen saturation (SaO2) and arterial partial pressure of oxygen (PaO2) in both groups were higher than before treatment, and the levels of arterial partial pressure of carbon dioxide (PaCO2) were lower than before treatment, in addition, the levels of SaO2 and PaO2 in the observation group were higher than those in the control group, and the level of PaCO2 was lower than that in the control group, the difference were statistically significant (P<0.05).There was no statistically significant difference in the incidence of adverse reactions between the two groups (P>0.05).Conclusion Ambroterol assisted cefaclor in the treatment of acute bronchitis in children is beneficial to improve clinical efficacy, and has a good effect on inflammatory symptoms and blood gas indexes, with fewer adverse reactions.
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