Effect of Fuyankang Capsules Combined with Metronidazole on Clinical Symptoms and Vaginal Microenvironment in Patients with Bacterial Vaginitis
Objective To explore the effect of using fuyankang capsules as an adjunct to metronidazole treatment for patients with bacterial vaginitis(BV).Methods A total of 64 BV patients who visited the gynecology department of Jinxiang County People's Hospital from May 2021 to June 2023 were selected as the study objects and randomly divided into a control group and an observation group,with 32 patients in each group.The control group was treated with metronidazole alone,while the observation group was treated with a combination of fuyankang capsules and metronidazole for 2 weeks.The clinical efficacy,symptom disappearance time,vaginal microenvironment,incidence of adverse reactions,and recurrence between two groups were compared.Results The total effective rate of the observation group was 93.75%,which was higher than 71.88%of the control group,the difference was statistically significant(P＜0.05).The disappearance time of external genital itching,vaginal odor,and abnormal increase in vaginal discharge in the observation group were shorter than those in the control group,and the differences between the groups were statistically significant(P＜0.05).After treatment,the observation group showed better microbial density and diversity than the control group,with statistically significant differences between the groups(P＜0.05).There was no statistically significant difference in the incidence of adverse reactions between the two groups(P＞0.05).The recurrence rate of 6.25%in the observation group,which was lower than 28.13%of the control group,the difference was statistically significant(P＜0.05).Conclusion The use of fuyankang capsules combined with metronidazole in the treatment of BV patients can shorten the time for symptom disappearance,improve the vaginal microenvironment,reduce the recurrence rate,and have high safety.
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