Effect of Standard Large Bone Flap Decompression Under Microscope on Cerebral Hemodynamics and Complications in Patients with Craniocerebral Injury
Objective To investigate the effects of standard large bone flap decompression under microscope on cerebral hemodynamics and complications in patients with craniocerebral injury.Methods A total of 82 patients with craniocerebral injury admitted to the hospital from January 2020 to September 2023 were selected as the study objects,and they were divided into a control group and an observation group according to random number table method,with 41 cases in each group.The control group was treated with traditional large bone flap decompression,and the observation group was treated with standard large bone flap decompression under microscope.The cerebral hemodynamic index,serological index,intracranial pressure,conscious state and complications were compared between the two groups.Results Seven days after operation,the mean transit time and peak time of the observation group were(2.04±0.25)s and(13.05±1.22)s,which were shorter than(2.89±0.31)s and(15.24±1.25)s of the control group,respectively.Cerebral blood flow and cerebral blood volume were(33.52±3.48)mL/(100 g·min)and(2.57±0.32)mL/100 g in the observation group,respectively,which higher than(26.89±3.12)mL/(100 g·min)and(2.15±0.28)mL/100 g of the control group,respectively,the differences between the groups were statistically significant(P＜0.05).The levels of hypersensitive C-reactive protein,tumor necrosis factor-α and human monocyte chemoattractant protein-1 in the observation group were(7.68±1.13)mg/L,(10.32±1.22)μg/L and(215.24±20.36)ng/L,respectively,which were lower than(9.25±1.17)mg/L,(13.47±1.28)μg/L,(254.71±25.89)ng/L of the control group,and the differences between the two groups were statistically significant(P＜0.05);the intracranial pressure in the observation group was(10.12±1.09)mmHg,which was lower than(13.07±1.22)mmHg in the control group,and the State of consiciousness score was(14.52±1.19)points,which was higher than(12.63±1.04)points in the control group,the differences between the two groups were statistically significant(P＜0.05).There was no significant difference in the incidence of complications between the two groups(P＞0.05).Conclusion Standard large bone flap decompression under microscope is effective in the treatment of patients with craniocerebral injury,which can reduce the cerebral hemodynamic damage,avoid the overreaction of the body inflammation,improve the condition of patients,and is safe and feasible.
Craniocerebral injuryStandard large bone flap decompression under microscopeCerebral hemodynamicsComplication
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