Clinical Effect of Carboprost Tromethamine Combined with Balloon Placement in the Treatment of Placenta Previa Postpartum Hemorrhage
Objective To investigate the clinical effect of carboprost tromethamine combined with balloon placement in the treatment of placenta previa postpartum hemorrhage.Methods A total 72 placenta previa patients with postpartum hem-orrhage admitted to Chengwu County People's Hospital from January 2018 to December 2021 were selected as the study ob-jects and were divided into a control group and an observation group according to random number table method,with 36 cases in each group.Uterine balloon placement was performed in both groups.On this basis,the control group was treated with oxy-tocin,and the observation group was treated with carboprost tromethamine.The hemostatic effect,bleeding situation,coagula-tion function and vital signs of the two groups were compared.Results The total effective rate of hemostasis in the observa-tion group was 94.44%,which was higher than 77.78%in the control group,the difference was statistically significant(P＜0.05).The postpartum blood loss at 2,6,12 and 24 h in the observation group were(385.25±34.16)mL,(658.41±50.24)mL,(862.41±75.41)mL and(1089.65±105.25)mL,respectively,which were less than(425.35±45.41)mL,(708.63±52.47)mL,(928.47±80.36)mL and(1254.63±125.74)mL in the control group,the differences between the groups were statistically significant(P＜0.05).After 24 h of treatment,the prothrombin time and activated partial thromboplastin time in the observation group were(11.53±1.22)s and(37.05±3.12)s,respectively,which were shorter than(13.42±1.25)s and(40.18±3.85)s in the control group,the differences between the two groups were statistically significant(P＜0.05).After 24 h of treatment,the systolic blood pressure and diastolic blood pressure in the observation group were higher than those in the control group,and the heart rate was slower than that in the control group,the differences between the two groups were statistically significant(P＜0.05).Conclusion Carboprost tromethamine combined with balloon placement has better hemostatic effect,can reduce postpartum blood loss,improve coagulation function,and stabilize heart rate and blood pressure in placenta previa patients.
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