Comparison the Clinical Effect and Safety of High-Flow Nasal Cannula Oxygen Therapy with Continuous Positive Airway Pressure Ventilation in the Treatment of Bronchiectasis with Pulmonary Infection
Objective To compare the efficacy of High-Flow Nasal Cannula Oxygen Therapy(HFNC)and continuous positive airway pressure ventilation(CPAP)in the treatment of bronchiectasis(BE)with pulmonary infection.Methods A total of 86 patients with BE with pulmonary infection admitted to Tai'an Central Hospital Affiliated to Qingdao University from January 2022 to September 2023 were selected as the study objects and divided into a control group and an observation group according to random number table method,with 43 cases in each group.The control group received CPAP and the observation group received HFNC.Both groups were treated for 2 weeks.The clinical efficacy,arterial blood gas analysis indexes and complications were compared between the two groups.Results The total effective rate of the observation group was 95.35%,which was higher than 79.07%of the control group,the difference was statistically significant(P＜0.05).The incidence of complications in the observation group was 4.65%,which was lower than 18.60%in the control group,the difference was statistically significant(P＜0.05).After treatment,the partial pressure of oxygen in the observation group was(86.95±6.13)mmHg,which was higher than(79.53±5.20)mmHg in the control group,and the partial pressure of carbon dioxide was(37.59±2.67)mmHg,which was lower than(45.24±3.20)mmHg in the control group,the differences between the two groups were statistically significant(P＜0.05).Conclusion HFNC can better improve the level of arterial blood gas analysis indexes in BE patients with pulmonary infection,and the complications are less.
BronchiectasiaPulmonary infectionComplicationsArterial blood gas analysis
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