Therapeutic Effect of the Combination of Xiao'er Feike Granules and Terbutaline Sulfate in the Treatment of Acute Bronchopneumonia in Children and Its Impact on Symptom Improvement Time
Objective To explore the effect of the combination of Xiao'er Feike Granules and Terbutaline Sulfate on children with acute bronchopneumonia.Methods A total of 86 children with acute bronchopneumonia admitted to Lanling County People's Hospital from June 2020 to September 2023 were selected as the research objects and randomly divided into a control group and an observation group using a random number table method,with 43 cases in each group.The control group received nebulized inhalation solution of terbutaline sulfate,while the observation group received an additional dose of Xiao'er Feike Granules on the basis of the control gorup.Compare the clinical efficacy,symptom improvement time,inflammatory factors,and adverse reactions between the two Groups.Results The total effective rate of treatment in the observation group was higher than that in the control group,and the difference was statistically significant(P＜0.05).The time for the observation group's body temperature to return to normal,the time for the disappearance of pulmonary wheezing,and the time for the disappearance of cough and sputum were all shorter than those of the control group,and the differences between the groups were statistically significant(P＜0.05).Before treatment,there was no statistically significant difference in the levels of high-sensitivity C-reactive protein(hs-CRP),interleukin-8(IL-8),and tumor necrosis factor-α(TNF-α)between the two groups(P＞0.05);After treatment,the levels of CRP,IL-8,and TNF-α in the observation group were lower than those in the control group,and the differences between the groups were statistically significant(P＜0.05).There was no statistically significant difference in the incidence of adverse reactions between the two groups(P＞0.05).Conclusion The combination of Xiao'er Feike Granules and Terbutaline Sulfate in the treatment of acute bronchopneumonia in children can enhance the therapeutic effect,significantly shorten the recovery time of clinical symptoms,relieve inflammatory reactions in pediatric patients,and have good safety.
Acute bronchopneumoniaXiao'er Feike GranulesTerbutaline sulfateCurative effectSymptom improve-ment time
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