首页|金水宝联合缬沙坦治疗慢性肾小球肾炎的临床效果研究

金水宝联合缬沙坦治疗慢性肾小球肾炎的临床效果研究

扫码查看
目的 探讨金水宝联合缬沙坦治疗慢性肾小球肾炎的效果.方法 选取 2022 年3 月—2023 年 3 月于我院接受治疗的 100 例慢性肾小球肾炎患者为研究对象,根据随机数字表法将其分为对照组和观察组,各50 例.对照组采用缬沙坦治疗,观察组在对照组基础上联合金水宝治疗.比较两组的临床疗效、肾功能指标、血脂水平及不良反应发生情况.结果 观察组治疗总有效率为 96.00%,高于对照组的 84.00%,差异有统计学意义(P<0.05).治疗 8周后,观察组24h尿蛋白、血肌酐水平均低于对照组,肾小球滤过率高于对照组,组间差异有统计学意义(P<0.05);观察组三酰甘油、总胆固醇水平均低于对照组,组间差异有统计学意义(P<0.05).观察组不良反应发生率与对照组比较,差异无统计学意义(P>0.05).结论 金水宝联合缬沙坦治疗慢性肾小球肾炎可显著改善患者的肾功能和血脂水平,且不会增加不良反应发生率.
Clinical Effect Study of Jinshuibao Combined with Valsartan in the Treatment of Chronic Glomerulonephritis
Objective Exploring the effect of Jinshuibao combined with valsartan in the treatment of chronic glomeru-lonephritis.Methods Selecting 100 patients with chronic glomerulonephritis who received treatment in our hospital from March 2022 to March 2023 as the research subjects,they were divided into a control group and an observation group using a random number table method,with 50 cases in each group.The control group was treated with valsartan,and the observation group combined with Jinshuibao treatment on the basis of the control group.The clintcal efficacy,renal function indexes,blood lipid levels and adverse effects were compared between the two groups.Results The total effective rate of the observa-tion group was 96.00%,which was higher than the control group's 84.00%,and the difference was statistically significant(P<0.05).After 8 weeks of treatment,the 24-hour urinary protein and blood creatinine levels in the observation group were lower than those in the control group,and the glomerular filtration rate was higher than that in the control group,and the dif-ferences between the groups were statistically significant(P<0.05);the levels of triglycerides and total cholesterol in the obser vation group were lower than those in the control group,and the difference between the groups were statistically significant(P<0.05).The incidence of adverse reactions in the observation group was not statistically significant compared to the control group(P>0.05).Conclusion The combination of Jinshuibao and valsartan in the treatment of chronic glomerulonephritis can significantly improve patients'renal function and blood lipid levels,without increasing the incidence of adverse reactions.

Chronic glomerulonephritisJinshuibaoValsartanRenal functionBlood lipid level

周杰

展开 >

金乡县人民医院肾内科,山东济宁 272200

慢性肾小球肾炎 金水宝 缬沙坦 肾功能 血脂水平

2024

反射疗法与康复医学

反射疗法与康复医学

ISSN:
年,卷(期):2024.5(17)