Effect of Tonglin Cupai Decoction Combined with Tamsulosin in the Treatment of Residual Stones after Percutaneous Nephrolithotripsy
Objective To explore the effect of Tonglin Cupai Decoction combined with Tamsulosin in the treatment of residual stones after percutaneous nephrolithotripsy(PCNL).Methods A total of 80 patients with residual stones after PCNL surgery admitted to our hospital from October 2021 to October 2023 were selected as the research subjects.They were randomly divided into a control group and a combination group using a random number table method,with 40 cases in each group.The control group was treated with tamsulosin,while the combined group was treated with Tonglin Cupai Decoction combined with tamsulosin.Compare the therapeutic effects,traditional Chinese medicine syndrome scores,inflammatory factors[interleukin-6(IL-6),C-reactive protein(CRP),tumor necrosis factor-α(TNF-α)]and adverse reactions between the two groups.Results The total effective rate of the combination group was higher than that of the control group,and the difference was statistically significant(P＜0.05).Before treatment,there was no statistically significant difference in the scores of traditional Chinese medicine syndromes between the two groups(P＞0.05);after treatment,the combination group had lower scores of traditional Chinese medicine symptoms such as abdominal pain/low abdominal distension,short and red urine frequency,unbearable astringency/dripping discomfort,and aversion to cold and fever compared to the control group,and the differences between the groups were statistically significant(P＜0.05).Before treatment,there was no statistically significant difference in IL-6,CRP,and TNF-α levels between the two groups(P＞0.05);after treatment,the levels of IL-6,CRP,and TNF-α in the combination group were lower than those in the control group,and the differences between the groups were statistically significant(P＜0.05).There was no statistically significant difference in the incidence of adverse reactions between the two groups(P＞0.05).Conclusion The combination of Cupai Decoction Tang and Tamsulosin can improve the symptoms of patients with residual stones after PCNL surgery,reduce inflammatory reactions,promote stone excretion,and treat safely and effectively.
Percutaneous nephrolithotripsyPostoperative residual stonesTonglin Cupai Decoction TamsulosinTherapeutic effectTraditional Chinese Medicine Syndrome PointsInflammatory factors
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