Effect of Cardiac Rehabilitation Training Combined with Tirofiban and Ticagrelor on Cardiac Function and Myocardial Injury Indexes in Patients with Acute Myocardial Infarction
Objective To investigate the effects of cardiac rehabilitation training combined with tirofiban and ticagrelor on cardiac function and myocardial injury indexes in patients with acute myocardial infarction(AMI).Methods Eighty patients with AMI admitted to Longkou People's Hospital from June 2022 to June 2023 were selected as the research objects,and were divided into the observation group(n=40)and the control group(n=40)according to random number table method.The control group was treated with tirofiban and ticagrelor,and the observation group was treated with cardiac rehabilitation training combined with tirofiban and ticagrelor,both groups received continuous treatment for 8 weeks.The clinical efficacy,cardiac function and myocardial injury indexes were compared between the two groups.Results The total effective rate of the observation group was 95.00%,which was higher than 80.00%of the control group,the difference was statistically significant(P＜0.05).Before treatment,there were no significant differences in the levels of cardiac function indexes between the two groups(P＞0.05);after treatment,the cardiac output and left ventricular ejection fraction of the observation group were higher than those of the control group,and the left ventricular end-systolic diameter and left ventricular end-diastolic diameter of the observation group were shorter than those of the control group,the differences between the groups were statistically significant(P＜0.05).Before treatment,there were no significant differences in the levels of myocardial injury indexes between the two groups(P＞0.05);after treatment,the levels of serum cardiac troponin I、creatine kinase-MB、brain natriuretic peptide and N-terminal pro-brain natriuretic peptide in the observation group were lower than those in the control group,and the differences between the groups were statistically significant(P＜0.05).Conclusion Cardiac rehabilitation training combined with tirofiban and ticagrelor can effectively improve the cardiac function indexes of AMI patients,reduce myocardial injury,improve the therapeutic effect,and is safe and reliable.
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