Comparison of the Effects of Ultra Early Intravenous Thrombolysis and Arterial Thrombolysis in Patients with Acute Cerebral Infarction
Objective To explore the application effect of ultra early intravenous thrombolysis and arterial thrombolysis in patients with acute cerebral infarction(ACI). Methods A total of 84 ACI patients admitted to our hospital from April 2021 to May 2023 were selected as the research objects and randomly divided into a control group and an observation group,each with 42 cases,using a random number table method. The control group was treated with ultra early intravenous thrombolysis,while the observation group was treated with ultra early arterial thrombolysis. Compare the National Institutes of Health Stroke Scale (NIHSS) score,fibrinogen (FIB),prothrombin time (PT),and thrombin time (TT),and adverse reactions were compared between the two groups. Results After 72 hours of treatment,the NIHSS score of the observation group after treatment was (7.76±0.87) points,lower than (12.25±1.46) points in the control group,and the difference was statistically significant(P<0.05);the FIB level in the observation group was (3.96±0.41)g/L,which was higher than (2.33±0.34)g/L in the control group,the PT and TT were (12.33±1.96)s and (16.33±2.34)s,respectively,which were shorter than(14.55±2.68)s and (18.26±2.85)s in the control group,and the differences between the groups were statistically significant(P<0.05). The incidence of adverse bleeding events in the observation group was 4.76％,which was lower than 19.05％ in the control group,and the difference was statistically significant (P<0.05). Conclusion Compared to ultra early intravenous thrombolysis,ultra early arterial thrombolysis can better improve neurological and coagulation function in ACI patients,and the incidence of adverse reactions is low,which is worthy of clinical application.
Acute cerebral infarctionUltra early intravenous thrombolysisArterial thrombolysisNeurological functionCoagulation function
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