Comparison of Efficacy and Safety Between Neuroendoscopy and Small Window Craniotomy for Hematoma Evacuation for the Treatment of Basal Ganglia Cerebral Hemorrhage
Objective To compare the effect of neuroendoscopy and small window craniotomy for hematoma evacuation in the treatment of basilar ganglia cerebral hemorrhage. Methods Eighty four patients with basal ganglia cerebral hemorrhage admitted to Ju County People's Hospital from September 2020 to September 2023 were selected as the study objects,and were divided into a control group and an observation group according to random number table method,with 42 cases in each group. The control group underwent small window craniotomy for hematoma evacuation,and the observation group underwent neuroendoscopic hematoma removal. The surgical indexes,neurological function,neurotrophic factors,quality of life and complications were compared between the two groups. Results The intraoperative blood loss in the observation group was (175.31±18.72)mL,which was less than (246.75±23.59)mL in the control group,the operation time and hospital stay were (146.83±9.22)min and (10.34±1.97)d,respectively,which were shorter than (189.76±11.46)min and (13.45±2.36)d in the control group,and the differences between the groups were statistically significant (P<0.05). After 1 month of surgery,the National Institute of Health Stroke Scale score of the observation group was (11.25±1.21) points,which was lower than (15.31±1.59) points of the control group,while the levels of brain-derived neurotrophic factor,insulin-like growth factor-1 and nerve growth factor were (4.96±1.22)ng/mL,(114.37±9.25)µg/L and (147.25±15.31)pg/mL,respectively,which were higher than (4.30±0.95)ng/mL,(105.29±7.31)µg/L and (134.51±13.95)pg/mL of the control group,and the differences between the groups were statistically significant (P<0.05);the scores of physical function,psychological function,social function and material life status in the generic quality of life inventory-74 in the observation group were (78.95±5.31) points,(79.96±5.22) points,(79.84±5.39) points and (80.31±5.42) points,respectively,which were higher than (69.83±4.46) points,(71.35±4.19) points,(70.58±4.23) points and (72.59±4.59) points of the control group,and the differences between the groups were statistically significant (P<0.05). The incidence of complications in the observation group was 4.76％,which was lower than 21.43％ in the control group,and the difference was statistically significant (P<0.05). Conclusion Neuroendoscopic hematoma removal has the advantages of less injury and complications,which can improve the nerve function,increase the level of neurotrophic factor and improve the quality of life of patients with basal ganglia cerebral hemorrhage.
Basal ganglia cerebral hemorrhageNeuroendoscopySmall window craniotomy for hematoma evacuationComplicationsQuality of life
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