Effect of Mufangji Decoction Combined with Etonocoxib on Dampness-Heat Accumulation Type of Acute Gouty Arthritis and the Level of Inflammatory Factors in Patients
Objective To analyze the effect of Mufangji decoction combined with etonocoxib on acute gouty arthritis(AGA)with dampness-heat accumulation type.Methods A total of 90 patients with AGA dampness-heat accumulation type admitted to Renhuai People's Hospital from July 2021 to August 2022 were selected as the research objects,and were divided into a control group and an observation group according to random number table method,with 45 cases in each group.The control group was treated with etonocoxib,and the observation group was treated with Mufangji decoction on the basis of the control group,both groups were treated for 2 weeks.The clinical efficacy,traditional chinese medicine syndrome score,inflammatory factor level and occurrence of adverse reactions were compared between the two groups.Results The total effective rate of the observation group was 97.78%,which was higher than 80.00%of the control group,the difference was statistically significant(P﹤0.05).After treatment,the scores of traditional chinese medicine syndrome in the observation group were lower than those in the control group,and the differences between the groups were statistically significant(P﹤0.05);the levels of interleukin-6,C-reactive protein and tumor necrosis factor-α in observation group were lower than those in control group,and the differences between the groups were statistically significant(P﹤0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P﹥0.05).Conclusion In the treatment of patients with AGA dampness-heat accumulation type,Mufangji decoction combined with etonocoxib can alleviate joint pain and reduce the level of inflammatory factors,and it is safe and feasible.
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