Prevention of Postpartum Hemorrhage in Patients with Placental Abruption after Cesarean Section by Combination of Carboprost Tromethamine and Oxytocin
Objective To investigate the effect of carboprost tromethamine combined with oxytocin on preventing postpartum hemorrhage in patients with placental abruption after cesarean section.Methods Select 86 patients with placental abruption after cesarean section admitted to Linyi Maternal and Child Health Hospital from January 2021 to January 2023 were selected as the research objects,and were divided into a control group and an observation group according to random number table method,with 43 cases in each group.The control group was treated with oxytocin,and the observation group was treated with carprost tramine on the basis of the control group.Compare the amount of postpartum hemorrhage,the occurrence of postpartum hemorrhage,coagulation function indicators,the height of the uterine fundus after delivery and the occurrence of adverse reactions between the two groups.Results The amounts of postpartum hemorrhage at 30 minutes,2 hours and 24 hours after delivery in the observation group were less than those in the control group,and the incidence of postpartum hemorrhage rate was 2.33%,which was lower than 18.60%in the control group,and the differences between the groups were statistically significant(P﹤0.05).At 24 hours after delivery,the activated partial thromboplastin time in the observation group was(27.21±4.63)s,which was shorter than(32.34±4.98)s in the control group,the plasma fibrinogen level was(3.04±0.97)g/L,which was lower than(3.84±1.17)g/L in the control group,the differences between the groups were statistically significant(P﹤0.05).At 2 hours and 24 hours after delivery,the fundal height of observation group were lower than those of control group,the differences between the groups were statistically significant(P﹤0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P﹥0.05).Conclusion In the treatment of patients with placental abruption and cesarean section,the carboprost tromethamine,tramine and oxytocin can enhance the curative effect,improve the coagulation function and fundal contraction,and effectively prevent postpartum hemorrhage,reduce the amount of postpartum hemorrhage,with high safety.
Placental abruptionCesarean sectionCarboprost tromethamineOxytocinCoagulation functionAmount of hemorrhage
万方数据
