Effects of Flupentixol and Melitracen Combined with Betahistine on the Degree of Dizziness and Vestibular Function in Patients with Residual Dizziness after Reduction of Benign Paroxysmal Positional Vertigo
Objective To investigate the effect of flupentixol combined with melitracen and betahistine in patients with residual dizziness after reduction of benign paroxysmal positional vertigo(BPPV).Methods A total of 84 patients with residual dizziness after reduction of BPPV in Jinxiang County People's Hospital from October 2020 to October 2023 were selected as the research objects,and were divided into a control group and an observation group according to random number table method,with 42 cases in each group.The control group was treated with betahistine mesylate and the observation group was treated with flupentixol melitracen tablets on the basis of the control group,both groups were treated for 2 months.The clinical efficacy,dizziness degree,vestibular function and adverse reactions were compared between the two groups.Results The total effective rate of the observation group was 95.24%,which was higher than 80.95%of the control group,and the difference was statistically significant(P﹤0.05).Before treatment,there was no significant difference in Dizziness Handicap Inventory(DHI)and Vestibular Symptom Index(VSI)scores between the two groups(P﹥0.05);after treatment,DHI and VSI scores in the observation group were lower than those in the control group,and the differences between the groups were statistically significant(P﹤0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P﹥0.05).Conclusion The flupentixol and melitracen combined with betahistine in the treatment of residual dizziness after reduction of BPPV has a significant effect,which is conducive to reducing the degree of dizziness and improving the vestibular function of patients,and has good safety.
Residual dizziness after reduction of benign paroxysmal positional vertigoFlupentixol and melitracenBetahistineDegree of dizzinessVestibular function
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