首页|腹腔镜手术联合地屈孕酮对子宫内膜异位症患者性激素水平及复发率的影响

腹腔镜手术联合地屈孕酮对子宫内膜异位症患者性激素水平及复发率的影响

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目的 探讨腹腔镜手术联合地屈孕酮对子宫内膜异位症(EMs)患者性激素水平及复发率的影响.方法 选取枣庄市峄城区人民医院 2022 年 3 月—2023 年 10 月收治的 84例EMs患者为研究对象,按随机数字表法将其分为对照组和观察组,各 42 例.对照组行腹腔镜下子宫内膜异位囊肿剥除术治疗,观察组在对照组基础上联合地屈孕酮治疗.对比两组的临床疗效、性激素水平、疼痛程度、复发情况.结果 观察组治疗总有效率为 97.62%,高于对照组的80.95%,差异有统计学意义(P﹤0.05).治疗后,观察组血清卵泡刺激素、促黄体生成素、雌二醇水平均低于对照组,下腹痛、痛经、性交痛评分均低于对照组,复发率低于对照组,组间差异有统计学意义(P﹤0.05).结论 腹腔镜手术联合地屈孕酮治疗EMs的疗效显著,可以调节性激素水平,缓解疼痛症状,降低复发率.
Effect of Laparoscopic Surgery Combined with Dydrogesterone on Sex Hormone Levels and Recurrence Rate in Patients with Endometriosis
Objective Exploring the effect of laparoscopic surgery combined with dydrogesterone on sex hormone levels and recurrence rate in patients with endometriosis(EMs).Methods A total of 84 patients with EMs admitted to Yicheng District People's Hospital of Zaozhuang City from March 2022 to October 2023 were selected as the research subjects,according to the random number table method,they were divided into a control group and an observation group,with 42 cases in each group.The control group underwent laparoscopic endometriosis cyst removal for treatment,while the observation group received combined treatment with dydrogesterone on the basis of the control group.Compare the clinical efficacy,sex hormone levels,pain severity,and occurrence of recurrence between two groups.Results The total effective rate of the observation group was 97.62%,which was higher than 80.95%in the control group,the difference was statistically significant(P﹤0.05).After treatment,the levels of serum follicle stimulating hormone,luteinizing hormone,and estradiol in the observation group were lower than those in the control group.The lower abdominal pain,dysmenorrhea,and sexual intercourse pain were lower than those in the control group,and the recurrence rate was lower than that in the control group,the differences between the groups were statistically significant(P﹤0.05).Conclusion Laparoscopic surgery combined with dydrogesterone has significant therapeutic effects on EMs,as it can regulate sex hormone levels,alleviate pain symptoms,and reduce recurrence rates.

EndometriosisLaparoscopic surgeryDydrogestoneSex hormonePainRecurrence rate

张艳君、孙鸿

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枣庄市峄城区人民医院妇产科,山东 枣庄 277300

子宫内膜异位症 腹腔镜手术 地屈孕酮 性激素 疼痛 复发率

2024

反射疗法与康复医学

反射疗法与康复医学

ISSN:
年,卷(期):2024.5(19)