ST段抬高性急性心肌梗死患者血浆瘦素浓度的变化
The Change of Plasma Leptin Concentration in Patients with ST-segment Elevation Acute Myocardial Infarction
黄日忠1
作者信息
摘要
目的:揭示ST段抬高性急性心肌梗死(STEAMI)患者血浆瘦素(leptin)浓度与住院期间主要不良心脏事件发生的相关性.方法:采集80例ST段抬高性AMI患者及40例健康体检正常者的静脉血,检测血浆leptin浓度,进行相关统计分析.结果:STEAMI患者住院期间主要不良心脏事件发生22例(27.5%),血浆leptin浓度较健康人显著升高(P<0.01).血浆leptin浓度是住院期间主要不良心脏事件发生的独立危险因素(P<0.01),对预测住院期间主要不良心脏事件发生有显著临床价值(P<0.01).结论:STEAMI患者血浆leptin浓度显著升高,其浓度测定有助于判断住院期间主要不良心脏事件的发生.
Abstract
Objective To investigate the relationship of plasma leptin concentration with occurrence of major adverse cardiac e-vent in patients with ST-segment elevation AMI during the hospitalization. Methods Venous blood of 80 patients and 40 healthy subjects were collected. Plasma leptin concentration was determined. Statistical analysis was undergone. Results Major adverse cardiac event occurred in 22 (27.5% ) cases. Plasma leptin level showed obviously higher in the patients than that of healthy subjects(P ＜ 0.01). Plasma leptin level was a risk factor of occurrence of major adverse cardiac event (P＜0.01) and predicted of happening with marked clinical value( P ＜ 0.01). Conclusion Plasma leptin concentration is enhanced in patients with ST-segment elevation acute myocardial infarction, and its determination can help to judge the occurrence of major adverse cardiac event during the hospitalization.
关键词
瘦素/急性心肌梗死/主要不良心脏事件Key words
leptin/acute myocardial infarction/major adverse cardiac event引用本文复制引用
出版年
2013
NETL
NSTL
维普
万方数据