Objective This study aimed to explore the correlativity between the level of interleukin-18(IL-18) in plasma and the outcomes of the patients with intracerebral hemorrhage. The change of plasma IL-18 and prognosis on patients were analysed statistically. Methods Eighty patients with intracerebral hemorrhage were included in our group. Concentration of IL-18 in plasma was measured with EUSA. Results Plasma IL-18 was highly associated with CCS score, hematoma volume and presence of intraventricular hemorrhage of patients (all P＜0.01), identified as a independent risk factor of 1 -year mortality(OR = 1.328, 95% CI = 1.017～ 2.682, P ＜ 0.01) , and predicted 1 -year mortality with the high sensitivity and specificity( P ＜ 0.01). Conclusion Interleukin-18 is obviously correlated with prognosis of intracerebral hemorrhage, and its clinical determination will be helpful for the early to evaluate the mortality of intracerebral hemorrhage.
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NSTL
维普
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