首页|糖尿病并发大血管病变患者sCD163与oxLDL-Ab检测的临床价值

糖尿病并发大血管病变患者sCD163与oxLDL-Ab检测的临床价值

Clinical Value of sCD163,oxLDL-Ab Detecting in Diabetic Macroangiopathy

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目的:探讨老年2型糖尿病(DM2)患者血清可溶性单核-巨噬细胞血红蛋白清道夫受体(sCD163)和抗氧化型低密度脂蛋白抗体(oxLDL-Ab)与大血管病变的关系.方法:测定 189例DM2患者及50例正常对照者sCD163和oxLDL-Ab水平,189例DM2患者分为大血管病变组(120例)与无大血管病变组(69例),比较三组间sCD163和oxLDL-Ab水平,并进行相关性分析.结果:与正常对照组比较DM2组sCD163与oxLDL-Ab水平较高、DM合并大血管病变组sCD163与oxLDL-Ab水平高于DM无血管病变组,各组间有显著性差异(P<0.05,P<0.05),且sCD163与oxLDL-Ab水平呈正相关(r=0.45,P<0.05).结论:sCD163与oxLDL-Ab与DM2大血管病变的发生发展密切相关,且联检可对早期动脉硬化的诊断具有重要的指导意义.
Objective To explore the elderly type 2 diabetes mellitus (DM2) patients on serum soluble macrophage hemoglobin scavenger receptor (sCD163) and oxidized low density lipoprotein antibody (oxLDL-Ab) and its relationship with macrovascular diseases. Methods sCD163 and oxLDL-Ab were measured in 189 diabetics and SO healthy controls 189 patients with diabetes mellitus, divided into large vascular lesion group (120 cases) and no major vascular lesion group (69 cases) , a comparison of three groups with sCD163 and oxLDL-Ab level, and the analysis of were made correlation. Results Compared to normal group, the diabetes group sCD163and oxLDL-Ab levels were higher, DM with large blood vessel lesion group sCD163and axLDL-Ab levels higher than those in DM without vascular lesion group, each group manifested statistical significance (P<0.05,P<0.05), and sCD163and axLDL-Ab levels are positively correlated (r=0.45, P<0.05). Conclusion sCD163and axLDL-Ab and diabetic macrovasciuar disease occurrence is closely related to the development and combined detection of early arteriosclerosis diagnosis provides important guiding significance.

diabetes mellitusvascular lesionssoluble macrophage hemoglobin scavenger receptoroxidized low density lipoprotein antibody

赵荣泽、赵中强

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浙江省江山市人民医院,324100

糖尿病 大血管病变 可溶性单核巨噬细胞血红蛋白清道夫受体 氧化型低密度脂蛋白抗体

2013

放射免疫学杂志
同济大学

放射免疫学杂志

CSTPCD
影响因子:0.508
ISSN:1008-9810
年,卷(期):2013.26(1)
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