The Relationship Between the Adherence Activity of Erythrocyte Complement Receptor 1(CR 1) and Serum TGF-β1 Levels in Patients with Chronic Hepatitis C
Objective To explore the correlativity between changes of adheremce activity of erythrocyte CR1 and serum TGF-β1 levels in patients with chronic hepatic C. Methods Erythiocyte CR1 adherence activity was detected with erythrocyte immune function test and serum TGF-p, level with ELLSA in 32 patients with chronic hepatic C and compared to 35 normal healthy controls. Results The erythrocyte GR1 adherence activity in patients with chronic hepatic C showed significantly lower than that controls(P ＜0. 01) , While the serum TGF-β1 level was markedly higher than that in controls(P＜0.01). The change of CR1 adherence activity was closely correlated with the change of serum TGF-β1 level. Conclusion Change of erythrocyte CRl adherence activity was closely correlated with the serum TGF-β1. Also, provides certain clinical value to predict the severity of pathosis, pathogeny and development
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