妊高征患者血清Hcy、hs-CRP和IL-10检测的临床评估
Clinical Evaluation of Measurement of Changes of Serum Hcy, hs-CRP and IL-10 Levels in Patients with Pregnancy Induced Hypertension
李卓1
作者信息
- 1. 江苏省沭阳仁慈医院妇产科,223600
- 折叠
摘要
目的:探讨妊高征(PIH)患者血清Hcy、hs-CRP、IL-10水平的变化及临床意义.方法:分别应用免疫法、免疫比浊法和放免法对68例PIH患者(其中重度PIH 31例,轻度PIH 37例)进行血清Hcy、hs-CRP和IL-10检测与35名正常孕妇作比较.结果:PIH患者血清Hcy、hs-CRP和IL-10水平均非常显著地高于正常妊娠组(P<0.01),重度PIH组又明显高于轻度PIH组(P<0.01),且血清Hcy水平与hs-CRP、IL-10呈正相关(r=0.6712、0.7018,P<0.01).结论:检测PIH患者血清Hcy、hs-CRP和IL-10水平的变化对密切监视病情的严重程度、病情发展均有重要的临床价值.
Abstract
Objective To explore the clinical significance of changes of serum Hcy, hs-CRP and IL-10 levels in patients with pregnancy induced hypertension ( PIH). Methods Serum Hcy( with immunoassay) , serum hs-CRP( with immne turbidinietry) , serum IL-10 (with RIA) levels were measured in 68 cases (31 cases severe PIH, 37 light PIH) and 35 normal controls. Results Serum Hey, hs-CRP, IL-10 levels were significantly higher than those in controls(P <0. 01). Severe PIH were more significant than light PIH(P<0.01). Serum Hcy levels were positively correlated with serum hs-CRP, IL-10 levels(r =0.6712, 0.7018, P <0. 01). Conclusion Changes of serum Hcy, hs-CRP and IL-10 levels to monitor the severity and progress of diseases might be of important clinical values in patients with PIH.
关键词
妊高征/同型半胱氨酸/超敏C-反应蛋白/白细胞介素-10Key words
pregnancy induced bypertension(PIH)/homocystein( Hcy)/higher sensitive-reactive protein( hs-CRP)/IL-10引用本文复制引用
出版年
2013
NETL
NSTL
维普
万方数据