CA19-9、CA50、CA242和TSGF联检对胰腺癌的诊断价值
Diagnostic Value of Combined Measurement of Serum CA19-9, CA50, CA242 and TSGF in Patients with Pancreatic Cancer
秦海峰1
作者信息
- 1. 江苏省昆山市第一人民医院放免科,215300
- 折叠
摘要
目的:探讨联检肿瘤标志物CA19-9、CA50、CA242和TSGF在胰腺癌诊断中的应用价值.方法:选取2008年7月~2011年10月来我院体检、就诊以及住院的患者共160人,进行了CA19-9、CA50、CA242和TSGF联检,其中85例为临床明确诊断的胰腺癌患者,32例为慢性胰腺炎患者,43例为正常人群.结果:胰腺癌患者血清CA19-9、CA50、CA242和TSGF水平明显高于正常对照组和慢性胰腺炎患者(P＜0.05).对于胰腺癌的诊断,四项联检使得诊断的敏感性明显提升,高达94.1%,而特异性则无明显改变,为70.6%.结论:联检血清CA19-9、CA50、CA242和TSGF对胰腺癌的诊断及鉴别诊断具有一定的临床意义.
Abstract
Objective To explore the diagnostic value of combined measurement of serum CA19-9, CA50, CA242 and TSGF in patients with pancreatic cancer. Methods Serum CA19-9, CA50, CA242 and TSGF levels were measured in 85 patients with pancreatic cancer, 32 patients with chronic pancreatitis and 43 normal controls. Results The serum concentrations of CA19-9, CASO, CA242 and TSGF in 85 patients with pancreatic cancer were obviously higher than those in controls (P <0.05) . Combined determination of the four markers elevate the sensitivity (94.1% ) but no more changes of the specificity (70.6% ) significantly in diagnosing the pancreatic cancer. Conclusion Combined detection of serum CA19-9, CA50, CA242 and TSGF levels can be clincally useful in improving diagnostic and differential diagnostic value for patients with pancreatic cancer.
关键词
糖类抗原19-9/糖类抗原50/糖类抗原242/肿瘤特异性生长因子/胰腺癌Key words
carbohydrate antigen 19-9 (CA19-9)/carbohydrate antigen 50 (CA50)/carbohydrate antigen 242 (CA242)/tumor specific growth factor (TSGF)/pancreatic cancer引用本文复制引用
出版年
2013
NETL
NSTL
维普
万方数据