乳腺癌患者手术前后血清CA15-3、SA和SIL-2R检测的临床意义
Clinical Significance of Measurement the Changes on Serum CA15-3, SA and SIL-2R Levels Both Before and After Operation in Patients with Breast Cancer
方海俊 1何雄平 1骆婷婷1
作者信息
- 1. 浙江省义乌市中心医院检验科,322000
- 折叠
摘要
目的:探讨乳腺癌患者手术前后血清CA15-3、SA和SIL-2R水平的变化及临床意义.方法:应用放射免疫分析、分光光度法和酶联法对31例乳腺癌患者进行手术前后血清CA15-3、SA和SIL-2R检测,并与35例正常人作比较.结果:乳腺癌患者在手术前血清CA15-3、SA和SIL-2R水平均非常显著地高于正常人组(P＜0.01),手术3个月后则与正常人组比较无显著性差异(P＞0.05).结论:乳腺癌患者血清CA15-3、SA和SIL-2R含量的变化与疾病的发生和发展密切相关.
Abstract
Objective To explore the clinical relevance of changes on Berum CA1S-3, SA and SIL-2R levels both before and after operation in patients with breast cancer. Methods Serum CA15-3(with RIA) , serum SA(with spectrometry) and SIL-2R(with ELISA) levels were determined both before and after operation in 31 patients with breast cancer as well as 35 normal controls. Results Before operation the serum levels of CA15-3, SA and S1L-2R in patients with breast cancer were significantly higher than those of controls(P<0.01). 3 mouths after operation the levels dropped markedly to approaching normal vs controls(P>0.05). Conclusion The serum CA15-3, SA and SIL-2R in patients with breast cancer closely related to the development and progression of the diseases.
关键词
乳腺癌/糖类抗原15-3/唾液酸/白细胞介素-2受体Key words
breast cancer/carbohydrate antigen 15-3(CA15-3)/sialic acid(SA)/interleukin-2 receptors (SIL-2R)引用本文复制引用
出版年
2013
NETL
NSTL
维普
万方数据