NSTEMI患者血清IL-6、cTnI和TNF-α检测的临床评价
Clinical Evaluation of Changes on Serum IL-6, cTnI and TNF-αLevels in Patients with Non-ST-Segment Elevation Myocardial Infarction(NSTEMI)
包杰1
作者信息
- 1. 江苏省连云港市第二人民医院心脏功能检查科,222002
- 折叠
摘要
目的:探讨非ST抬高型急性心肌梗死(NSTEMI)患者血清IL-6、cTnI和TNF-α水平的变化的临床意义.方法:应用放射免疫分析和生化法对62例怀疑NSTEMI患者进行了血清IL-6、cTnI和TNF-α检测,并根据临床诊断分成观察组和对照组,进行统计学分析.结果:NSTEMI患者血清IL-6、cTnI和TNF-α水平均非常显著地高于对照组.且血清IL-6水平与cTnI和TNF-α水平呈显著正相关(r=0.5782、0.6024,P＜0.01).结论:血清IL-6、cTnI和TNF-α水平升高与NSTEMI的预测、诊断和预后均有一定的临床价值.
Abstract
Objective To explore the significance of changes on the levels of serum TL-6, cTnl and TNF-α in patients with suspicious non-ST-segment elevation myocardial infarction(NSTEMI). Methods Serum IL-6,TNT-α(with RIA) and serum cTnI(mth bi ochemistry) levels were measured in 62 patients who were suspected NSTEMI statistical analysis of observation group and control group divided by clinical diagnosis was conducted. RssultS The levels of serum IL-6, cTnl and TNF-α were significantly higher than those incontrols(P<0.01). The levels of serum IL-6 was obviously positive correlated with the levels of cTnl, TNF-α(r= 0.5782,0.6024, P< 0.01). Conclusion The changes of levels of serun IL-6, cTnI and TNF-a closely associated with NSTEMI, and might be of certain clinical value of prediction, diagnosis and prognosis in patients with NSTEMI.
关键词
急性心肌梗死/非ST抬高型急性心肌梗死(NSTEMI)/白细胞介素-6/肌钙蛋白I/肿瘤坏死因子-αKey words
acute myocardial infarction, non-ST-segment elevation myocardial in?arction( NSTEMI)/interleukin-6(IL-6)/cardiac troponin I(cTnI)/tumor necrosis factor-a(TNF-α)引用本文复制引用
出版年
2013
NETL
NSTL
维普
万方数据