ACI患者血清NSE和血浆D-D、Fb相关性的分析
Study on the correlative Analysis of Serum NSE and Plasma D-dimer,Fibrinogen in Patients with Acute Cerebral Infarction
杜莉 1王绪虎1
作者信息
摘要
目的:叙述了急性脑梗死(ACI)患者血清神经元特异性烯醇化酶(NSE)和血浆D-二聚体(D-D)、纤维蛋白原(Fb)水平的变化及其之间的相关性.方法:采用化学发光法和免疫比浊法对34例ACI患者进行了血清NSE和血浆D-D、Fb检测,并与35名正常健康人作比较.结果:ACI患者血清NSE和血浆D-D、Fb水平均非常显著地高于正常人组(P<0.01).血清NSE与血浆D-D、Fb水平呈正相关(r=0.4928、0.5012,P<0.01)结论:血清NSE和血浆D-D、Fb与ACI的发生、发展密切相关.三者联检对ACI的预防、治疗和预后均具有重要的临床意义.
Abstract
Objective To explore the levels of serum NSE and plasma D-dimer( D-D) , fibrinogen (Fb) in patients with acute cerebral infarction and the correlation among such laboratory items. Methods Serum NSE(with CLIA),plasma D-D and Fb(with im munoturhidimetry) levels were determined in 34 patients with acute cerebral infarction and 35 normal health; controls . Results Serum NSE and plasma D-D, Fb levels in the patients with ACI were significantly higher then those in controls (P<0.01). Serum NSE level was positively correlated with D-D, Fb leveb(r= 0.4928, 0.5012. ,P<0.0l). Conclusion The serum NSE, plasma D-D and Fb levels are closely related to the occurrence of patients with ACI. The combined detection of NSE, D-D and Fb provides important clinical significance in the prevention, treatment and prognosis of ACI.
关键词
急性脑梗死/神经元特异性烯醇化酶/D-二聚体/纤维蛋白原Key words
acute cerebral infarction(ACI)/neuron specific enolase(NSE)/D-dimer(D-D)/fibrinogen(Fb)引用本文复制引用
出版年
2013
NETL
NSTL
维普
万方数据