Objective To observe the relationship between the common serum biochemical indexes and the degree of liver fibrosis, and expected to find indexes for predicting the obvious liver fibrosis. Methods One hundred and sixty cases were divided into five groups (S0, S1, S2, S3 and S4) according to the results of pathological biopsy. The levels of the common serum biochemical indexes were detected and the correlation between indexes and liver fibrosis degree were analyzed. After the fibrotic levels were classified in two stratifications, which were non-significant fibrosis ( S0-S1) and significant fibrosis ( S2 -S4) , independent risk factors for predicting liver fibrosis were screened from the common serum biochemical indexes. Results It was observed that the most serum biochemical indexes were significantly correlated with the clinical stages of liver fibrosis. Single factor analysis showed that the AUC > 0.7 for cho-linesterase and serum prealbumin, and cholinesterase was identified by multivariate logistic regression analysis as independent factors of fibrosis. Conclusion More serum biochemical indexes were significantly correlated with the clinical stages of liver fibrosis and cholinesterase can be used to predicting the obvious liver fibrosis.
NETL
NSTL
维普
万方数据
