PLC患者手术前后血清TGF-α、TGF-β1和CA19-9检测的临床意义
Clinical Significance of Measurement the Changes on Serum TGF-α TGF-β1 and CA19-9 Levels Both Before and After Operation in Patients with Primary Liver Cancer
伏开新 1姚加平 1刘春燕 1李静1
作者信息
- 1. 江苏省灌云县人民医院检验科,222200
- 折叠
摘要
目的:探讨了原发性肝癌(PLC)患者手术治疗前后血清TGF-α、TGF-β1和CA19-9水平的变化及临床意义.方法:应用放射免疫分析对30例PLC患者进行了手术治疗前后血清TGF-α、TGF-β1和CA19-9检测.并与35名正常健康人作比较.结果:PLC患者在手术治疗前血清TGF-α、TGF-β1和CA19-9水平非常显著地高于正常人组(P<0.01),手术治疗6个月后则与正常人组比较无显著性差异(P>0.05).结论:检测PLC患者手术治疗前后血清TGF-α、TGF-β1和CA19-9水平的变化在临床上具有重要的价值.
Abstract
Objective To explore the clinical significance of measurement the changes on serum TGF-α, TGF-β1 and CA19-9 levels both before ant after operation in patients with primary liver cancer. Methods Serum TGF-α,TGF-β1 and CA19-9(with RIA) levels were determined in 30 patients with primary liver cancer( PLC) both before after operation and compared to 35 normal controls. Results Before operation ,the serum TGF-α,TGF-β1 and CA19-9 levels in the patients were remarkably higher than these in controls (P<0.01) .6 months after operation. The differences between the levels in patients and controls were not significant (P >0.05). Conclusion Changes of serum TGF-α,TGF-β1 and CA19-9 levels both before and after operation might be of important clinical value in patients with primary liver cancer clinically.
关键词
原发性肝癌/转化生长因子-α/转化生长因子-β1/糖类抗原19-9Key words
primary liver cancer(PLC)/transforming growth factor-α(TGF-α)/transforming growth factor-p/(TGF-β1) .car-bohydrate antigenl9-9( CA19-9)引用本文复制引用
出版年
2013
NETL
NSTL
维普
万方数据