摘要
目的:探讨急性脑梗死(ACI)患者血清甲状腺激素及TSH水平变化与同型半胱氨酸(Hcy)水平的相关性.方法:应用化学发光法和酶免法对33例ACI患者进行了血清TT3、TT4、TSH、FT3、FT4和Hcy检测,并与35名正常健康人作比较.结果:ACI患者血清TT3、FT3水平非常显著地低于正常人组(P<0.01).而TT4、FT4、TSH水平与正常人组比较无显著性差异(P＞0.05).血清Hcy水平显著地高于正常人组(P＜0.01),血清Hcy水平与TT3、FT3水平呈高度负相关(r=-0.5011、-0.4912,P<0.01).结论:检测ACI患者血清甲状腺激素及TSH水平,可用于ACI的辅助诊断,具有一定的临床实用价值.
Abstract
Objective To explore the changes of thyroid hormone levels in patients with acute cerebral infarction and its correlation to homocysteine. Methods Serum TT3, FT3, TT4, FT4 ,TSH(with CLIA) , serum Hcy(with ELISA)levels were determined in 33 patients with acute cerebral infarction and 35 normal healthy individually served as control. Resulte Serum TT3 , FT3 levels proved apparently lower than those in controls (P<0.01), but serum TT4, FT4, TSH showed no significance ((P >0.05) , serum Hcy level presented markedly higher than that in controls ( P < 0. 01). Serun Hcy level was negative correlated with TT3 , FT3 levels ( r = -0.5011, - 0.4912 ,P < 0.01). Conclusion Detection of serum thyroid hormone levels in patients with acute cerebral infarction might be helpful in diagnosis of acute cerebral infarction and provides certain clinical value.
NETL
NSTL
维普
万方数据