血硒、GPX与外周血CD94在反复自然流产患者水平变化的临床意义
Clinical Relevance of the Changes on Selenium , GPX and CD94 in Peripheral Blood in Patients with RSA
张亚斌 1贾翠英 2代云峰2
作者信息
- 1. 浙江省宁波市鄞州第二医院妇产科,315000
- 2. 齐齐哈尔医学院第二附属医院检验科,161006
- 折叠
摘要
目的:检测原因不明反复自然流产(RSA)患者血硒、谷胱甘肽过氧化物酶(GPX)及外周血中CD94水平变化,探讨该类变化对反复自然流产发病中的作用.方法:采集RSA患者、正常妊娠妇女和非妊娠妇女(各35例)外周血检测硒、GPX与CD94含量.结果:RSA患者血硒、GPX水平均比正常妊娠妇女和非妊娠妇女呈现显著低下(P<0.01),CD94水平均亦比正常妊娠妇女和非妊娠妇女低(P<0.05).结论:血硒、GPX 与CD94在外周血中的低表达可能与反复自然流产的发病和病理生理过程有关.
Abstract
Objective Testing the changes on selenium , GPX and CD94 in peripheral blood for recurrent spontaneous abortion (RSA) patients, in order to explore such changes on function in RSA. Methods To test the levels of selenium , GPX and CD94 in peripheral blood in 35 cases of pregnant women , 35 cases of non-pregnant women , and 35 cases of RSA patients . Results The levels of selenium and GPX in RSA patients proved markedly lower than those in pregnant women and non-pregnant women(P<0.01); the level of CD94 in RSA patients expressed lower than that in pregnant women and non-pregnant women(P<0.Q5). Conclusion Low levels of selenium , GPX and CD94 in peripheral blood might be related to the development and pathophy Biological process in RSA.
关键词
流产/自然/血硒/谷胱甘肽过氧化物酶/CD94Key words
abortion/spontaneous/selenium/GPX/CD94引用本文复制引用
出版年
2013
NETL
NSTL
维普
万方数据