Objective:This study was aimed to investigate the value of native T1-mapping and readout segmentation of long variable echo-trains diffusion weighted imaging(RESOLVE-DWI)in differentiating parotid gland tumors.Methods:169 patients with parotid gland tumors who underwent native T1-mapping and RESOLVE-DWI confirmed by pathology from June 2018 to August 2022 were retrospectively analyzed,including 85 patients with pleomorphic adenomas(PAs),32 patients with Warthin tumors(WTs),and 52 patients with malignant parotid gland tumors(MPGTs).The mean T1 and apparent diffusion coefficient(ADC)values of the lesions between groups were calculated and analyzed.Receiver operating characteristic(ROC)curve analysis was conducted and the area under the curve(AUC)was calculated to evaluate the diagnostic performance of T1-value,ADC value,and the combination of them(T1+ADC).The differences in AUCs between T,and ADC was analyzed using Delong test.Results:Overall,there were significant differences in T1 and ADC values among three groups(all P＜0.001),pairwise comparison showed that T1 and ADC values were statistically signifi-cant(all P＜0.001).PA exhibited the highest T,and ADC values,followed by MT,WT was the lowest.The AUC of T1 and ADC in differentiating PA and WT,PA and MT,WT and MT were 0.914 and 0.997,0.664 and 0.869,0.835 and 0.695,respectively.Delong test showed that there were no signi-ficant differences in AUCs between T1 and ADC(all P＞0.05).The AUC of T1+ADC in differentia-ting PA and WT,and PA and MT was higher than that of T1-value(1.000 vs.0.914 and 0.873 vs.0.664,both P＜0.001).The AUC of T1+ADC in differentiating WT and MT was higher than that of T1(0.895 vs.0.835,P＜0.001)and ADC(0.895 vs.0.695,P＜0.001).Conclusion:Both native T1-map-ping and RESOLVE-DWI all can be used to quantitatively differential diagnosis common parotid gland tumors.Combination of the two methods can further improve the diagnostic efficiency.
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