Objective:To analyze the imaging appearance and clinicopathologic features of nodu-lar fasciitis(NF).Methods:The clinical data,imaging and pathological materials of 47 patients with NF confirmed by postoperative pathology were analyzed retrospectively.There were 25 males and 22 fe-males,aged from 7 to 69 years,with an average age of(38.7+12.4)years.Results:There were 47 le-sions in 47 cases.36.2%(17/47)were located in the upper limbs,27.7%(13/47)in the trunk,21.3%(10/47)in the head and neck,12.8%(6/47)in the lower limbs and 2.1%(1/47)in the breast.All 47 patients were classified into four subtypes:Myxoid,cellular,fibrous and mixed subtype were 19,12,14 and 2 cases respectively.The center cells of myxoid lesions were tightly packed and interspersed with liquefying zone,all the myxoid lesions showed a slight low signal intensity on T1WI and high signal in-tensity on T2WI,and 7 lesions showed an"inverted target"sign.The cells of cellular lesions were ar-ranged closely and capillaries were distributed evenly;the lesions demonstrated homogenous signal in-tensity on MRI and homogeneously marked enhancement after contrast administration in 5 cases.The center of fibrous lesions were abundant in collagen with a slight low signal intensity on T2WI in corre-sponding region,and the"central fibrotic scar"sign can be demonstrated in 7 cases.Conclusion:Ima-ging appearance manifestations of NF bear certain relationship with the course of disease and the his-tological subtypes,the"fascia tail"sign and"inverted target"sign have a certain diagnostic signifi-cance.