首页|3.0T非对比增强MR冠脉成像在节段水平对血管显著性狭窄的诊断效能评估

3.0T非对比增强MR冠脉成像在节段水平对血管显著性狭窄的诊断效能评估

Evaluation of diagnostic efficacy of 3.0T non-contrast-enhanced MR coronary angiography for significant vascular stenosis at the segmental level

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目的:基于冠脉血管节段水平评估3.0T自由呼吸非对比增强全心冠状动脉MR成像在血管显著性狭窄方面的诊断效能.方法:2021年5月至2023年6月连续纳入于河南中医药大学第一附属医院拟行冠状动脉造影(CAG)的患者98例,患者CAG术前一周行3.0T无对比剂MR冠脉成像(CMRA).完成两项检查后,以CAG为"金标准"对CMRA在检测冠状动脉显著性狭窄(管腔直径减少≥50%)方面的能力进行了基于血管节段水平的评估.结果:基于血管节段水平CMRA对血管显著性狭窄的诊断效能为敏感度75.42%、特异度96.50%、阳性预测值82.41%、阴性预测值94.76%、准确度92.74%;除 LCX2 外,LM、LAD1、LAD2、LAD3、LCX1、RCA1、RCA2、RCA3 节段的 ROC 曲线下面积都大于0.75;LAD3、LCX2节段的诊断结果受图像质量影响相对较大.结论:3.0T非对比增强MR冠脉成像是一项具有广阔应用前景的无创、无辐射冠状动脉成像技术,与CAG具有相似的诊断效能,可用于疑似冠心病患者冠状动脉显著性 狭窄的检测.
Objective:To evaluate the diagnostic efficacy of 3.0T free-breathing non-contrast-en-hanced whole-heart coronary artery MR imaging in significant vascular stenosis based on coronary ar-tery segment levels.Methods:From May 2021 to June 2023,98 patients scheduled for coronary angiog-raphy(CAG)at the First Affiliated Hospital of Henan University of Traditional Chinese Medicine were enrolled consecutively.All patients underwent 3.0T non-contrast-enhanced MR coronary angiog-raphy(CMRA)one week before CAG.Following both examinations,the ability of CMRA to detect significant coronary artery stenosis(lumen diameter reduction ≥50%)was evaluated at the vascular segment level,using CAG as the"gold standard".Results:The diagnostic efficacy of CMRA at the vas-cular segment level for significant vascular stenosis showed a sensitivity of 75.42%,specificity of 96.50%,positive predictive value of 82.41%,negative predictive value of 94.76%,and accuracy of 92.74%;Except for the LCX2 segment,the area under the ROC curve(AUC)for the LM,LAD1,LAD2,LAD3,LCX1,RCA1,RCA2,and RCA3 segments was greater than 0.75.The diagnostic results for the LAD3 and LCX2 segments were greatly affected by the image quality.Conclusion:3.0T non-contrast-enhanced MR coronary imaging is a promising non-invasive and radiation-free coronary ima-ging technique with diagnostic efficacy comparable to CAG,which can detect significant coronary ar-tery stenosis in patients with suspected coronary artery disease.

Coronary heart diseaseCoronary arterySignificant vascular stenosisMagnetic resonance angiographyCoronary angiography

邢威、贺俊景、孙杰梅、周丽格、张刚

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450000 郑州,河南中医药大学第一附属医院磁共振科

冠心病 冠状动脉 显著性狭窄 磁共振血管成像 冠状动脉造影

河南省中医药科学研究专项课题

2021JDZY023

2024

放射学实践
华中科技大学同济医学院

放射学实践

CSTPCD北大核心
影响因子:1.08
ISSN:1000-0313
年,卷(期):2024.39(9)