Application of two-dimensional speckle tracking imaging on right ventricular function in type 2 diabetes patients with metabolic risk stratification factors
Application of two-dimensional speckle tracking imaging on right ventricular function in type 2 diabetes patients with metabolic risk stratification factors
Objective:To investigate the clinical value of two-dimensional speckle tracking echo-cardiography(2D-STE)in evaluating the right ventricular function in type 2 diabetes patients with metabolic risk stratification.Methods:127 patients with diabetes in our hospital were gathered and stratified to 60 cases in the low-risk group(DM1)and 67 cases in the high-risk group(DM2)accord-ing to metabolic risk factors.At the same time,40 healthy volunteers of the same age and gender were selected as the control group.All subjects'entrance and clinical data on hypertension,triglycerides,and BMI,were collected.We performed routine echocardiography and a 2D-STE examination,analyzed the strain of the right ventricular free wall offline,and further performed a segmented analysis of the right ventricular free wall.The differences in parameters between the diabetes group and the normal control group,DM1 group,and DM2 group were compared.Results:The right ventricular free wall thickness,tricuspid ring systolic velocity,and right ventricular myocardial working index in the diabetes group were significantly increased compared with the control group,while the E/A value of the tricuspid valve,the absolute value of right ventricular free wall strain RVFWS,the absolute value of the right ventricular free wall strain in the base segment,middle segment,and apex segment were significantly decreased compared with the control group,with statistical difference(P＜0.05).The right ventricular free wall thickness and right ventricular myocardial working index in DM2 group were higher than those in DM1 group.The absolute values of the right ventricular free wall strain,middle and apex strains of the right ventricular free wall in DM2 group were significantly lower than those in DM1 group,with statistical significance(P＜0.05).ROC curve analysis showed that the efficiency of apical segment strain differentiation between DM1 and DM2 group was higher,with the Yoden index 0.389,the AUC 0.743(95％CI:0.657～0.829),the sensitivity 0.806,and the specificity 0.583.Conclusion:Two-dimensional spot tracking imaging parameters can timely detect the impairment of right ventricu-lar function in diabetic patients.The impairment of right ventricular function in diabetic patients with high metabolic risk factors is more serious.
关键词
2型糖尿病/心脏功能/右心室/超声检查/二维斑点追踪成像
Key words
Type 2 diabetes mellitus/Heart function/Right ventricle/Ultrasonography/Two-dimensional spot tracking imaging
维普
万方数据