Application of phase-contrast magnetic resonance image in dynamic changes of cerebrospinal fluid for type Ⅰ Chiari malformation patients with cough headache
Objective:To investigate the application value of PC-MRI in the dynamic changes of cerebrospinal fluid of type Ⅰ Chiari malformation patients with cough headache.Methods:A total of 39 patients with type Ⅰ Chiari malformation diagnosed in our hospital from September 2020 to May 2023 were collected.According to the cough headache symptoms,23 cases were divided into symptomatic group,and 16 cases for asymptomatic group,another 18 cases of normal control group were selected.All the patients and normal controls received PC-MRI examination.The region of interest was the ven-tral pons at the level of the foramen magnum,The peak cephalad flow velocity(Vumax),peak foot flow velocity(Vdmax),the proportion of cephalad flow time(Tu)and the proportion of foot flow time(Td)of cerebrospinal fluid(CSF)were obtained in symptomatic group,asymptomatic group and normal control group.Results:The peak cephalad flow velocity(Vumax)in symptomatic group,asymptomatic group and normal control group were(6.38±0.89)cm/s,(5.92+1.32)cm/s,(4.86±0.90)cm/s,while the peak foot flow velocity(Vdmax)were(5.87±1.01)cm/s,(5.71±1.32)cm/s,(4.62±0.83)cm/s,and the proportion of cephalad flow time(Tu)were(70.6±4.0)％,(58.7±3.2)％,(58.0±2.8)％,the proportion of foot flow time(Td)were(28.9±3.4)％,(41.2±3.3)％,(41.9±2.8)％,respectively.There were no significant differences in the peak cephalad velocity(Vumax)and peak foot velocity(Vdmax)between the symptomatic group and the asymptomatic group(P＞0.05),while the proportion of cephalad flow time(Tu)increased and the proportion of foot flow time(Td)decreased in the symptomatic group,with the significant differences(P＜0.01)compared to the a-symptomatic group.There were only statistical differences of the peak cephalad flow velocity(Vumax)and the peak foot flow velocity(Vdmax)between asymptomatic group and normal control group(P＜0.01),while the statistical differences in the peak cephalad flow velocity(Vumax),the peak foot flow velocity(Vdmax),the proportion of cephalad flow time(Tu)and the proportion of foot flow time(Td)between symptomatic group and normal control group were existed(P＜0.01).Conclusion:PC-MRI has a great value to understand the changes of CSF dynamics in type Ⅰ Chiari malformation patients with cough headache,which is helpful to understand the etiology of cough headache.
Magnetic resonance imagingChiari malformationHeadache disorders,primary
万方数据
维普
