Objective:To explore the value of color-coded multiphase CT angiography(mCTA)in assessing clinical outcome of acute ischemic stroke(AIS).Methods:The clinical data and imaging data of anterior circulation AIS patients were analyzed retrospectively.The patients were divided into a good prognosis group(91 cases,mRS＜3 points)and a poor prognosis group(86 cases,mRS ≥3 points)based on the 90 day modified Rankin scale(mRS)results.Collateral status score of the con-ventional mCTA,color-coded mCTA(including collateral filling dynamics score,extent score and com-mon score)which was assessed by a 3-point scale.The differences of the collateral status score of the conventional mCTA,color-coded mCTA were compared by x2 or Fisher exact test between the two groups.The differences of the volume of ischemic and infarct core which derived from CT perfusion(CTP)were compared by Mann-Whitney U between the two groups.The diagnostic value of CT pa-rameters on the clinical prognosis of AIS patients were analyzed by receiver operating characteristic curve(ROC).The impact of each parameter on the clinical prognosis of AIS patients was analyzed by multivariate Logistic regression analysis.Results:CT parameters were significant statistical differences between two groups(P＜0.05).A better collateral status score,a lower volume of ischemic and in-farct core in the good prognosis group were found.The ROC results showed that the diagnostic value of the color-coded mCTA score was similar to or higher than that of conventional mCTA score on the clinical prognosis of patients.And the collateral filling dynamics score(AUC=0.67)in predicting clinical prognosis is similar to the volume of ischemic(AUC=0.74)and infarct core(AUC=0.75)which derived from CTP(Z=1.552,P=0.121;Z=1.606,P=0.108).Logistic regression analysis showed that the collateral filling dynamics score and volume of infarct core are factors of clinical prog-nosis for patients[OR(95％CI)2.39(1.03～5.52),P=0.039;OR(95％CI)3.88(1.86～8.10),P＜0.001].Conclusion:The color-coded mCTA provide a high value in predicting the clinical prognosis of AIS patients on 90 days.The collateral filling dynamics score is a factor of clinical prognosis for pa-tients,and it can achieve similar to or better diagnostic efficacy when compared with conventional mC-TA and CTP.
万方数据
维普
