Objective:To analysis the clinical,CT and pathological features of bronchial adenoma(BA).Methods:The clinical,CT and pathological manifestations of 22 pathologically confirmed cases were reviewed and analyzed.Results:Of the 22 cases of BA,19 cases had detectable lesions on preoper-ative chest CT.5 of the 19 cases were solid,12 were ground-glass,and 2 were cystic.There were 8 males and 11 females,aged 36～82(60±12)years.15(78％)had no obvious respiratory symptoms.Fifteen cases(78.9％)had no obvious respiratory symptoms.BA was located in the subpleural region.The diameter of BA lesions in 19 cases was(9.24±1.22)mm,CT value was(-373.74±62.92)HU,shape was irregular in 15 cases,blurred borders were found in 10 cases,lobular sign was found in 3 ca-ses,burr sign or calcification was found in 1 case,vacuolar sign was found in 4 cases,pleural depression sign was found in 6 cases,abnormal air bronchus sign was found in 8 cases and abnormal vascular sign in 10 cases.Eight patients with BA underwent preoperative follow-up.2 had a diameter growth rate of 1～1.49mm/year,and the volume doubling time(VDT)of BA was(1063±272)days in 5 cases.10 of 22 cases(45％)had concomitant lung cancers.12 cases(80％)had intraoperative frozen references to BA.BA foci showed 100％expression of thyroid transcription factor 1(TTF-1),NapsinA,CK7,and CK7,andCK7 expression was 100％,and Ki-67 was 1％～2％.Conclusion:Patients with bronchiolar adenoma(BA)have atypical clinical symptoms,diverse imaging manifestations,and are prone to clini-cal misdiagnosis.
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