Study of dramatic reducing radiation dose of CT pulmonary angiography using artificial intelligence model-based iterative reconstruction with 70kV ultra-low tube voltage setting
Study of dramatic reducing radiation dose of CT pulmonary angiography using artificial intelligence model-based iterative reconstruction with 70kV ultra-low tube voltage setting
Objective:To explore the application value of dramatic reducing radiation dose of CT pulmonary angiography(CTPA)using artificial intelligence model-based iterative reconstruction(AI-IR)combined with 70kV ultra-low tube voltage setting.Methods:A total of 100 patients with suspec-ted pulmonary embolism or follow-up of pulmonary artery embolism were underwent CTPA and ran-domly divided into group A(100kVp)and group B(70kVp),hybrid iterative reconstruction(HIR)was used in group A,and HIR and AIIR were used in group B.Radiation doses were evaluated for group A and B.Background noise,signal-to-noise ratio(SNR)and contrast-to-noise ratio(CNR)of pulmonary artery on the HIR images in group A and those on the HIR and AIIR images in group B were evaluated,image quality of CTPA was graded on a 5-point scale.Results:Among the 100 pa-tients,10 patients were excluded because of respiratory motion artifacts or massive pleural effusion.Fi-nally,50 and 40 patients were included in group A and group B,respectively.The effective doses(ED)were(4.3±0.8)mSv in group A and(1.3±0.2)mSv in group B,compared to group A,the ED was decreased by 69.8％in group B(P＜0.001).The background noise was(19.2±3.7)HU,(28.1±4.4)HU and(13.7±6.5)HU on the HIR images in group A,the HIR and AIIR images in group B,respectively;the background noise on the AIIR images in group B was significantly lower than that on the HIR images in group A and B(P＜0.001).On the HIR images in group A,the SNR and CNR of right pulmonary were 21.5±5.9 and 18.8±5.6,and those of left pulmonary were 21.9±6.2 and 19.2±5.9,respectively;on the HIR images in group B,the SNR and CNR of right pulmonary were 19.4±3.7 and 17.2±3.5,and those of left pulmonary were 19.4±3.5 and 17.2±3.3,respectively;on the AIIR images in group B,the SNR and CNR of right pulmonary were 45.7±14.5 and 40.9±13.4,and those of left pulmonary were 46.0±14.6 and 41.1±13.6,respectively;the SNR and CNR of right and left pulmonary on AIIR images in group B were all significantly higher than those on HIR images in group A and B(P＜0.001).The subjective scores were 4.5±0.6,4.1±0.5 and 4.9±0.3 for the HIR images in group A,the HIR images and AIIR images in group B,respectively;the subjec-tive scores for the AIIR images in group B were significantly higher than those for the HIR images in group A and B(P＜0.001).Conclusion:The radiation dose of CTPA can be reduced significantly using AIIR combined with 70kV ultra-low tube voltage setting while image quality is better than the HIR image using 100kV tube voltage.
维普
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