首页|含硝酸盐的坚韧水凝胶辐射变色剂量计

含硝酸盐的坚韧水凝胶辐射变色剂量计

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在临床放射治疗实践中,如何迅速、安全、精确且经济地监测受照剂量或实施照射前的质量保证措施,始终是这一研究领域内的研究热点.本研究创新性地利用硝酸根离子与水辐解产生的自由基之间的反应作为剂量响应机制,选取硅胶辐射接枝丙烯酸复合凝胶作为基质材料,开发出一种具备高机械强度的坚韧辐射复合水凝胶剂量计.实验结果显示,在硝酸钠浓度为0.5 mol/L及甲酸钠浓度为2.5×10-3 mol/L的条件下,该水凝胶剂量计展现出了最佳的剂量响应线性相关性.此外,所制备的水凝胶剂量计不仅具备出色的抗穿刺性能、非脆性、耐高压能力以及机械性能的可调性,还在实际应用中表现出了非常好的时间稳定性,具有很好的潜在市场应用价值.
Tough nitrate-based radiation discoloration composite hydrogel dosimeter
In the clinical practice of radiotherapy,how to quickly,safely,accurately and economically monitor the irradiation dose or implement quality assurance measures before irradiation has always been a research hotspot in this research field.In this study,the reaction between nitrate ions and free radicals produced by water radiolysis was innovatively used as a dose-response mechanism.A radiation-grafted silica gel acrylic composite was selected as a matrix material to develop a tough radiation composite hydrogel dosimeter with high mechanical strength.The experimental results showed that the hydrogel dosimeter exhibited the best dose-response linear correlation under a sodium nitrate concentration of 0.5 mol/L and sodium formate concentration of 2.5×10-3 mol/L.In addition,the prepared hydrogel dosimeter not only exhibited excellent puncture resistance,non-brittleness,high pressure resistance,and adjustable mechanical properties,but also displayed impressive time stability in practical applications,indicating potential for commercialization.

Nitrate-based composite hydrogelHigh mechanical propertiesRadiation dosimeterRadiation therapy

田园、黄士堂、马骏

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中国科学技术大学核科学与技术学院 合肥 230026

北京大学生命科学学院 北京 100871

硝酸盐基复合水凝胶 高机械性能 辐射剂量计 放射治疗

2024

辐射研究与辐射工艺学报
中国科学院上海应用物理研究所

辐射研究与辐射工艺学报

CSTPCD
影响因子:0.527
ISSN:1000-3436
年,卷(期):2024.42(6)