Application of Cyclodextrin Polymers in Sample Pretreatment for Food Analysis
Cyclodextrin(CD)is a type of cyclic oligosaccharide comprising glucose molecules,and it possesses a large ring cavity that is hydrophilic on the exterior and hydrophobic on the interior,en-abling it to encapsulate a diverse range of guest molecules.Cyclodextrin-containing polymers(CDPs)are defined as a polymer derivative containing multiple cyclodextrin units constructed by chemical bonding of cyclodextrin molecules,which not only preserves the envelope recognition capabilities of cyclodextrin,but also exhibits enhanced mechanical strength,stability,and chemical adaptability as a polymeric entity.CDPs have a wide range of potential applications in sample pretreatment,their selective adsorption and separation,efficient removal of contaminants,and reproducible and envi-ronmentally friendly properties provide strong support for their applications in environmental protec-tion,food safety and other fields.This paper presents a generalization of the synthesis methods of dif-ferent CDPs and their applications in the field of sample preparation for food analysis,by combining with solid-phase microextraction,magnetic solid-phase extraction,stir bar extraction and other tech-niques.CDPs are able to effectively separate and enrich target analytes,including pesticide resi-dues,food additives and natural flavour components,in food.Additionally,it offers a summary of the current development status and future development trends of CDPs.