Advances in the Application of MOFs and COFs for the Selective Enrichment and Chromatographic Separation of Active Ingredients in Traditional Chinese Medicine
Metal-organic frameworks(MOFs)and covalent organic frameworks(COFs)possess ex-ceptional attributes,notably their remarkably extensive specific surface areas and adjustable pore siz-es,which greatly facilitate the selective enrichment and separation of target compounds.These unique properties have exhibited considerable potential in the field of active components derived from traditional Chinese medicine(TCM).This review elucidates the prevalent methodologies for synthesiz-ing MOFs and COFs,and delves into their applications,alongside composite materials,in the se-lective enrichment and chromatographic separation of active ingredients from a diverse array of Chi-nese medicinal matrices.Moreover,it examines the future prospects of these materials in identifying active components of TCM through the perspective of network pharmacology,providing valuable in-sights for the exploration and development of novel organic framework materials within the domain of efficacious constituents in TCM.
metal-organic frameworkscovalent organic frameworksactive ingredients of TCMselective enrichmentchromatographic separation