Development and application of organ-on-chip technology in the field of drug analysis
Organ-on-chip(OoC)is a ground-breaking biomedical engineering technique.This high-precision and high-accuracy microphysiological system offers benefits including high throughput,high analytical efficiency,low reagent consumption,fast detection speed,and high degree of automation and is considered as a promising tool for drug analysis.This review details the developmental process of OoC in recent years,introduces the applications of various OoC,such as liver chips,kidney chips,brain chips,gut chips,and multi-organ chips,in drug analysis,summarizes the significant challenges faced,and discusses the prospects of OoC,offering useful assistance and guidance for drug analysis by OoC.