首页|颍淮排石汤对上尿路结石术后残石排出的疗效分析

颍淮排石汤对上尿路结石术后残石排出的疗效分析

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通过前瞻性、随机、对照临床研究,分析中药方剂"颍淮排石汤"对输尿管软镜钬激光碎石术后残留结石的排出效果.选取 2020 年 4 月-2022 年 10 月我科行输尿管软镜钬激光碎石术后有结石残留的患者 161 例,按照数字表法随机分为对照组和中医治疗组,其中对照组 76 例,治疗组 85 例.对照组根据患者病情变化按需予以口服药物行抗感染、镇痛对症治疗;治疗组在对照组用药基础上加用中药方剂"颍淮排石汤"每日服用1剂,分 2 次水煎服用,共治疗 8 周.观察两组结石排出时间、结石排净时间、结石排净率、总有效率、中医证候变化、使用镇痛药物情况、尿白细胞转阴时间等指标.治疗 8 周后,治疗组的结石排净率为 91.8%,总有效率 95.3%,明显高于对照组的 78.9%、84.2%,差异有统计学意义(P<0.05);治疗组的结石排出时间和排净时间(5.50±1.55 天,22.88±5.34 天)均短于对照组(9.60±2.10 天,40.01±3.94 天,P<0.05);治疗组患者 2 周后中医证候评分低于对照组(P<0.05);治疗组患者应用镇痛药物的比例低于对照组(12.76%vs 30.91%,P<0.05),治疗组患者术后尿常规白血病转阴时间短于对照组(13.60±1.85 天vs 20.76±4.86 天,P<0.05).颍淮排石汤可以明显促进输尿管软镜钬激光碎石术后残留结石的排出,缩短排石时间,同时可以减少患者术后腰痛、血尿等症状,促进尿路感染的恢复.
Analysis of the efficacy of the stones excretion of residual stones by"Yinghuaipaishi decoction"after the flexible ureteroscopic holmium laser lithotripsy of upper urinary tract stones
Through prospective randomized controlled study,the Chinese medicine prescription"Yinghuaipaishi Decoc-tion"is analyzed for the discharge effect of residual stones after the flexible ureteroscopic holmium laser lithotripsy.From April 2020 to October 2022,161 patients with stone residues after flexible ureteroscopic holmium laser lithotripsy in our department were randomly divided into control group and traditional Chinese medicine treatment group according to the numerical table method,including 76 cases in the control group and 85 cases in the treatment group.The control group were given oral drugs for anti-infection and analgesic symptomatic treatment according to the changes of the patient's condition.The treatment group were given the traditional Chinese medicine"Yinghuaipaishi Decoction",1 dose 2 servings per day,plus the treatment done on the control group,for a total of 8 days.Of the two groups,stone discharge time,stone removal time,stone removal rate,total effec-tive rate,TCM syndrome changes,use of analgesic drugs,urinary leukocytes turning negative time and other indicators were ob-served.The measurement data are expressed as mean±standard deviation,using t-test.After 8 weeks of treatment,the stone ex-cretion rate of the treatment group was 91.8%,and the total effective rate was 95.3%,which was significantly higher than that of the control group(78.9%and 84.2%),and the difference was statistically significant(P<0.05).The stone expulsion time and clearance time in the treatment group(5.50±1.55 days,22.88±5.34 days)were shorter than those in the control group(9.60±2.10 days,40.01±3.94 days,P<0.05).After 2 weeks,the TCM syndrome score in the treatment group was lower than that in the con-trol group(P<0.05).The proportion of patients in the treatment group who received analgesic drugs was lower than that in the control group(12.76%vs 30.91%,P<0.05),and the time to turn negative for postoperative urine leukemia in the treatment group was shorter than that in the control group(13.60±1.85 days vs 20.76±4.86 days,P<0.05).The Yinghuaipaishi Decoction stone de-coction can significantly promote the discharge of residual stones after ureteral flexible holmium laser lithotripsy,shorten the stone expulsion time,reduce the symptoms of low back pain and hematuria in patients after surgery,and promote the recovery of urinary tract infection.

urinary stonesresidual stonesrandom control tests

梅国徽、王二朋、张怀伟、戴廷山

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阜阳市第二人民医院 泌尿外科,安徽 阜阳 236000

泌尿系结石 残留结石 随机对照试验

安徽省中医药传承创新科研项目

2020zcyb20

2024

阜阳师范大学学报(自然科学版)
阜阳师范学院

阜阳师范大学学报(自然科学版)

影响因子:0.263
ISSN:1004-4329
年,卷(期):2024.41(2)