Research Progress on Transition Metal Catalysts of tert-Butyl Sulfinamide
Since 1997,the Ellman research group has synthesized and separated optically pure chiral tert-butyl sulfinamide for the first time,which has been applied in the synthesis of transition metal catalysts.Due to the advantages of simple structure,easy synthesis,and good catalytic performance,transition metal catalysts based on tert-butyl sulfinamide have become a research hotspot in the field of asymmetric catalysis.Therefore,many research groups at home and abroad have been designing and synthesizing new tert-butyl sulfinamide transition metal catalysts,and study their potential application.In this review,we summarized the tert-butyl sulfinamide transition metal catalysts reported in the past ten years,which are classified according to the ligand coordination atoms and functional groups,and can be divided into four categories:tert-butyl sulfinamide-sulfur ligand,tert-butyl sulfinamide-phosphorus ligand,tert-butyl sulfinamide-olefin ligand,and other tert-butyl sulfinamide ligand(coordination atoms are S,N or S,O).The synthesis methods and applications of these catalysts are briefly described.
tert-butyl sulfinamidetransition metal catalystsasymmetric synthesis
NETL
NSTL
万方数据
