For some thick polyamide/spandex blended fabrics,80%formic acid method and dimethylfor-mamide method were used for quantitative analysis when 20%hydrochloric acid method was difficult to dis-solve nylon fiber.The results showed that 80%formic acid method had great damage to polyurethane fiber,and the test results of dimethylformamide method were stable and reliable,which could be used in combi-nation with 20%hydrochloric acid method based on the sample conditions.