Correlation Analysis between Ecological Factors and Main Efficacy Com-ponents in Dracocephalum tanguticum
The purpose of this study was to analyze the correlation between the main efficacy components of the Tibetan medicine Dracocephalum tanguticum and the ecological factors in the sampling area,and to screen the key factors affecting the accumulation of main efficacy components.D.tanguticum samples were collected from differ-ent producing areas in Gansu,Qinghai,Sichuan and Tibet,and the content of main efficacy components(p-hydrox-ybenzoic acid,cosmosiin,rosmarinic acid,betulin,betulinic acid,oleanolic acid and ursolic acid)were determined by HPLC(high performance liquid chromatography).The correlation between origin ecological factors and effica-cy component content was studied by factor analysis and stepwise regression analysis.The results showed that the rosmarinic acid was extremely significant negatively associated with precipitation in August(P<0.01);cosmosiin was extremely significant negatively associated with November precipitation(P<0.01);p-hydroxybenzoic acid,oleanolic acid and ursolic acid were all extremely significant negatively correlated with precipitation in the wettest quarter(P<0.01).The accumulation of the main effective components of D.tanguticum significantly decreased with the increase of origin precipitation,indicating that the key factor affecting its efficacy quality is precipitation of origin,among which the influence of summer precipitation is particularly prominent.