Advances of Cytochrome P450s in the Biosynthesis of Plant Secondary Metabolites
Cytochrome P450s are a type of superfamily of monooxygenases that are ubiquitous in nature,and have been praised as"versatile biocatalysts"because of their extensive participation in the biosynthesis of various secondary metabolites in plants.In recent years,more and more plant cytochrome P450 genes have been charac-terized with the development of high-through sequencing and molecular biology,and the relevant biosynthesis researches have got distinguished progresses.In this review,the structural features and catalytic mechanism of cytochrome P450s,as well as advances of plant cytochrome P450s in the biosynthesis of secondary metabolites are introduced.This review provides references for the discovery and characterization of plant cytochrome P450 enzymes,and also lays a basis for related biosynthesis and metabolic regulation researches.
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