3D Printing Strategies for Precise and Functional Assembly of Silk-based Biomaterials

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外文摘要：In recent years,significant progress has been made in both three-dimensional(3D)printing technologies and the exploration of silk as an ink to produce biocompatible constructs.Combined with the unlimited design potential of 3D printing,silk can be processed into a broad range of functional materials and devices for various biomedical applications.The ability of silk to be processed into various materials,including solutions,hydrogels,particles,microspheres,and fibers,makes it an excellent candidate for adaptation to different 3D printing techniques.This review presents a didactic overview of the 3D print-ing of silk-based materials,major categories of printing techniques,and their prototyping mechanisms and structural features.In addition,we provide a roadmap for researchers aiming to incorporate silk printing into their own work by summarizing promising strategies from both technical and material aspects,to relate state-of-the-art silk-based material processing with fast-developing 3D printing tech-nologies.Thus,our focus is on elucidating the techniques and strategies that advance the development of precise assembly strategies for silk-based materials.Precise printing(including high printing resolu-tion,complex structure realization,and printing fidelity)is a prerequisite for the digital design capability of 3D printing technology and would definitely broaden the application era of silk,such as complex bio-mimetic tissue structures,vasculatures,and transdermal microneedles.

外文关键词：

3D printingBiolnkBioprintingSilk fibroin

作者：

Xiaoliang Cui、Jun Zhang、Yan Qian、Siqi Chang、Benjamin J.Allardyce、Rangam Rajkhowa、Hui Wang、Ke-Qin Zhang

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作者单位：

National Engineering Laboratory for Modern Silk,College of Textile and Clothing Engineering,Soochow University,Suzhou 215123,China

Institute for Frontier Materials,Deakin University,Geelong,VIC 3216,Australia

基金：

National Natural Science Foundation of ChinaNational Natural Science Foundation of ChinaNatural Science Foundation of Jiangsu Province of ChinaNatural Science Foundation of the Jiangsu Higher Education Institutions of ChinaPriority Academic Program Development of Jiangsu Higher Education Institutions(PAPD)China National Textile and Apparel Council Key Laboratory for Silk Functional Materials and TechnologyOpening Project of Key Laboratory of Jiangsu Province for Silk Engineering,Soochow University

项目编号：

5187313452303043BK2021131723KJB430031KJS2168

出版年：

2024

DOI：

10.1016/j.eng.2023.09.022

工程(英文)

CSTPCDEI

ISSN：2095-8099

年,卷(期)：2024.34(3)