首页|Process,Material,and Regulatory Considerations for 3D Printed Medical Devices and Tissue Constructs
Process,Material,and Regulatory Considerations for 3D Printed Medical Devices and Tissue Constructs
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Three-dimensional(3D)printing is a highly automated platform that facilitates material deposition in a layer-by-layer approach to fabricate pre-defined 3D complex structures on demand.It is a highly promis-ing technique for the fabrication of personalized medical devices or even patient-specific tissue con-structs.Each type of 3D printing technique has its unique advantages and limitations,and the selection of a suitable 3D printing technique is highly dependent on its intended application.In this review paper,we present and highlight some of the critical processes(printing parameters,build orien-tation,build location,and support structures),material(batch-to-batch consistency,recycling,protein adsorption,biocompatibility,and degradation properties),and regulatory considerations(sterility and mechanical properties)for 3D printing of personalized medical devices.The goal of this review paper is to provide the readers with a good understanding of the various key considerations(process,material,and regulatory)in 3D printing,which are critical for the fabrication of improved patient-specific 3D printed medical devices and tissue constructs.
3D printingBioprintingBiofabricationMedical devicesTissue constructs
Wei Long Ng、Jia An、Chee Kai Chua
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Singapore Centre for 3D Printing(SC3DP),School of Mechanical and Aerospace Engineering,Nanyang Technological University,Singapore 639798,Singapore
Centre for Healthcare Education,Entrepreneurship and Research@SUTD(CHEERS),Singapore University of Technology and Design,Singapore 487372,Singapore
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